Parallel Brain Interaction Sensing Division
Director | Takemura Hiroshi : Professor, Department of Mechanical, Faculty of Science and Technology |
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Research Content | R & D of brain interaction between multiple individuals and within an individual another brain |
Objetcitves | Our goals is to break away from the conventional brain research and technology development focused on a single individual, creating a new brain research area analyzing the multiple brain interaction. |
Background and purpose of the division
This division was established to clarify how the brain activities of multiple individuals interact with each other in the process of social group formation, and the aim of the division is to supporting group formation and creating a society in which diverse individuals can live together in harmony. We would like to create a new academic research field, “Parallel Brain,” which will clarify the process of social group formation and interaction by focusing on the brains of multiple individuals, breaking away from conventional brain research and technology development that has focused on single individuals. By using brain research methods for synchronously (parallel) measuring the brain activity of multiple individuals (mice and humans) who form a group, and by proposing technologies for sensing and reproducing biological information based on brain research findings from our unique interdisciplinary field, we will be able to support social group formation and symbiosis in the online space. Furthermore, by using the same sensing technology in both mouse and human experiments, we aim to build a theoretical background for describing the interaction between multiple brains common to social animals using mathematical models.
Research Organization and Members
Introduction of research themes (excerpt)
There are several research themes in progress, some of which are introduced below.
Identification of a novel factor that promotes regeneration of injured nerve axons and analysis of its molecular functions
The physiological organization of the neural network in brains is a prerequisite for higher brain functions ranging from memory and decision to behavior and empathy. On the other hand, the central nerve axons of adult mammals have lost the ability to regenerate from injury, as shown by the pathology of spinal cord injuries caused by traffic accidents or falls from heights. Basic research to reinforce this loss of regenerative capacity and reconstruct the neural circuit has progressed rapidly in the last decade, and axon regeneration has been partially successful in mouse optic nerve. Nakamura and Koinuma have newly identified the TC10 G protein as a molecule that promotes axonal regeneration in the mammalian central nervous system. The regeneration factor TC10 was known to have the molecular function of membrane addition to the plasma membrane. In addition, TC10 has the ability of stabilizing microtubules at distal axons. This research has been done in collaboration with department Prof. Takemura and Segi.
Molecular mechanism of Autism Spectrum Disorder (ASD)
Autism spectrum disorder (ASD) encompasses a set of neurodevelopmental phenotypes that clinically present with impairments in social interaction and restricted, repetitive behaviors. Current studies suggest that copy number variations at chromosome location 3p26 – in particular a deletion spanning the CHL1, CNTN6 and CNTN4 genes – are a highly-penetrant risk factor for ASD. However, the molecular mechanisms by which genes at this locus mediate neuronal cognitive function and development still remain unknown. To understand potential neuronal mechanisms linking 3p26 deletions to ASD, we have generated the animal model to investigate behavioral and molecular phenotypes. We will use these animals to study how 3p26 loss-of-function impacts upon normal brain development and behaviors. This research has been done in collaboration with Drs. Segi-Nishida, Oguro-Ando, Saito, and Nakamura.
Future Development Goals
We will hold a number of public seminars and workshops to find a common language for researchers in multiple dimensions, educating the young investigator and students, increasing the integration of researchers.
Message
This division brings together researchers from both inside and outside the university in the field of the brain and neural information and systems to create an innovative academic field, “Parallel Brain,” originating from the University of Science. We aim to reveal how brain activity of multiple individuals interacts with each other.
Research Division
- Carbon Value Research Center
- Division of Advanced Urbanism and Architecture
- Academic Detailing Database Division
- Division of Nanocarbon Research
- Division of Colloid and Interface Science
- Chemical Biology Division Supported by Practical Organic Synthesis
- CAE Advanced Composite Materials and Structures Research Division
- Division of Nucleic Acid Drug Development
- Division of Synthetic Biology
- Renewable Energy Science & Technology Research Division
- Division of Ambient Devices Research
- Division of Biological Environment Innovation
- Statistical Science Research Division
- Department of MOT Strategy & Financial Engineering for Social Implementation
- Research Alliance for Mathematical analysis
- Division of Nano-quantum Information Science and Technology
- Research Group for Advanced Energy Conversion
- Development of superior cell and DDS for regenerative medicine
- Parallel Brain Interaction Sensing Division
- Division of Digital Transformation
- Modern Algebra and Cooperation with Engineering
Research Center
Joint Usage / Research Center
The Open Innovation Projects